Fertiscan is a comprehensive and innovative genetic test designed to identify the causes of infertility in both female and male partners who are experiencing difficulties in having children.
It has two lines of investigation: Fertiscan Female Infertility Panel and Fertiscan Male Infertility Panel. The first, dedicated to women, is available in two levels of analysis: a more comprehensive analysis that simultaneously examines 70 genes for the study of the main genetic causes associated with infertility and recurrent miscarriages, and a more targeted analysis for investigating specific genetic disorders.
Fertiscan Global Male Infertility Panel, on the other hand, is a test that simultaneously analyzes 50 genes to study the main genetic causes of male infertility.
FERTISCAN
Available panels
Fertiscan Global Male Infertility Panel
Fertiscan Global Female Infertility Panel
Fertiscan Primary ovarian insufficiency / Ovarian dysfunction NGS Panel
Fertiscan Ovarian dysgenesis NGS Panel
Fertiscan Preimplantation embryonic lethality - NGS Panel
Fertiscan Oocyte maturation defects NGS Panel
Fertiscan Miscarriage NGS Panel
Fertiscan Polycystic Ovary Syndrome NGS Panel
Fertiscan Ovarian Hyperstimulation Syndrome: response to ovarian stimulation
FERTISCAN
Who it's recommended for
Fertiscan is recommended in cases of:
Couples with a history of recurrent miscarriage
Couples with reproductive difficulties
Couples who have attempted assisted reproduction multiple times
Couples with hereditary infertility conditions
Couples who would like to try assisted reproduction
FERTISCAN
Analysis method
The genes included in the Fertiscan panels are fully sequenced at high depth of coverage using Next Generation Sequencing (NGS) technologies.
The analysis involves a complete study of the coding region of each gene (full exon sequencing) at high resolution. The obtained genetic sequences are interpreted through advanced bioinformatics analysis to identify any mutations associated with diseases in the analyzed genes.
Sensitivity and specificity > 99%.
Scientific publications in support
(1) Cioppi F, Rosta V, Krausz C. Genetics of Azoospermia; Int J Mol Sci. 2021.
(2) Biswas L, et al, Meiosis interrupted: the genetics of female infertility via meiotic failure.Schindler K; Reproduction. 2021.