Nutrifert is a predictive genetic test aimed at early identification of predispositions to female infertility and obstetric conditions that can be managed through targeted nutrition.
Nutrition and lifestyle have a significant impact on reproduction and fertility in humans, as they are essential for processes such as implantation, placental growth, angiogenesis, and the transfer of nutrients from the mother to the fetus. The interaction between nutrition and fertility is crucial for reproductive performance.
The relationship between ovulatory disorders and metabolic diseases such as diabetes suggests that dietary factors play an etiological role in certain types of infertility. Nutrifert investigates traits that play a significant role in the reproductive cycle and that can be managed through personalized dietary plans based on the genetic results of certain variants.
The investigated traits are:
predisposition toobesity
predisposition to gestational diabetes
predisposition to celiac disease
predisposition to polycystic ovary syndrome
predisposition toendometriosis
predisposition to recurrent miscarriages
search for variants in the FSH receptor
NUTRIFERT
Available panels
Nutrigenetics: Nutrifert
NUTRIFERT
Who it's recommended for
Nutrifert is aimed at women who are planning a pregnancy or who are experiencing difficulties in conceiving without a precise diagnosis or one related to the reproductive sphere.
NUTRIFERT
Analysis method
The test is performed using a blood sample or cells from the oral mucosa (swab). The sample is processed following a detailed laboratory protocol: DNA is isolated from nucleated cells and then amplified either by Real-Time PCR technology or through NGS analysis.
Scientific publications in support
(1) Knut et al., 1993. Gliadin-specitlc, HLA-DQ(crl*0501,~I*0201) Restricted T Cells Isolated from the Small Intestinal Mucosa of Celiac Disease Patients.
(2) Frayling et l., 2007. A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity.
(3) Sciurti ET AL., 2018. Genetic susceptibilty and celiac disease: what role do HLA haplotypes play?
(4) Zhao et al., 2020. Histamine Intolerance—A Kind of Pseudoallergic Reaction.
(5) Kim et al., 2017. A promoter variant of the APOA5 gene increases atherogenic LDL levels and arterial stiffness in hypertriglyceridemic patients.