Test for thrombophilia
The thrombophilia panels are screening tests for genetic polymorphisms associated with an increased risk of hereditary thrombophilia and the development of cardiovascular diseases.
The purpose of these panels is to determine individual risk profiles aimed at personalized treatment and early prevention of these diseases.
THROMBOPHILIA
Available panels
Thrombophilia Panel 15 Mutations
Thrombophilia Panel 4 Mutations
Thrombophilia Panel Recurrent Miscarriage
ACE - Angiotensin Converting Enzyme
AGT (M235T)
APO B
APO E (Genotyping)
Beta Fibrinogen, FGB (-455G-A)
Factor II - Prothrombin
Factor V (H1299R) R2
Factor V (Y1702C)
Factor V cambridge
Factor V Leiden
Factor XIII
Human Platelet Alloantigens (HPA)
MTHFR A1298C
MTHFR C677T
PAI-1
THROMBOPHILIA
Who it's recommended for
The thrombophilia tests are indicated in cases of:
Family history
Planning a pregnancy in women with a family or personal history of thrombosis
Before or during the use of oral contraceptives
Recurrent miscarriage
THROMBOPHILIA
Analysis method
Initially, an enzymatic reaction known as Polymerase Chain Reaction (PCR) is performed to amplify the DNA. This process allows for the in vitro amplification of a specific region of the molecule by copying it through various successive stages, ultimately generating millions of copies.
Subsequently, the PCR products obtained are subjected to automated sequencing analysis.
The mutation analysis is performed through a comparative analysis between the sequences obtained for the sample under examination and the normal sequences of the investigated genes, stored in the international database GeneBank.